7 insiders reported 55 Form 4 transactions for Lyra Therapeutics, Inc. (LYRA) over the past 18 months (most recent 2026-05-15). Recent activity: Smith W Bradford (Director) Sell 640 shares, Palasis Maria (Principal Executive Officer) Sell 2,000 shares, Cavalier Jason (Principal Financial Officer) Sell 667 shares, Cavalier Jason (Chief Financial Officer) Sell 769 shares, Palasis Maria (President & CEO) Sell 1,702 shares. Source: SEC Form 4.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-05-15 | Smith W Bradford | Director | Sell | 640 | $0 |
| 2026-04-03 | Palasis Maria | Principal Executive Officer | Sell | 2,000 | $0 |
| 2026-04-03 | Cavalier Jason | Principal Financial Officer | Sell | 667 | $0 |
| 2026-01-08 | Cavalier Jason | Chief Financial Officer | Sell | 769 | $2,584 |
| 2026-01-08 | Palasis Maria | President & CEO | Sell | 1,702 | $5,719 |
| 2025-11-13 | Perceptive LS (A), LLC | 10% Owner | Sell | 537 | $2,314 |
| 2025-11-13 | PERCEPTIVE ADVISORS LLC | 10% Owner | Sell | 4,783 | $20,615 |
| 2025-11-13 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | Sell | 4,783 | $20,615 |
| 2025-11-13 | Perceptive LS (A), LLC | 10% Owner | Sell | 4,783 | $20,615 |
| 2025-11-13 | EDELMAN JOSEPH | 10% Owner | Sell | 537 | $2,314 |
| 2025-11-13 | PERCEPTIVE ADVISORS LLC | 10% Owner | Sell | 537 | $2,314 |
| 2025-11-13 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | Sell | 537 | $2,314 |
| 2025-11-13 | Perceptive LS (A), LLC | 10% Owner | Sell | 28,597 | $111,528 |
| 2025-11-13 | EDELMAN JOSEPH | 10% Owner | Sell | 7,862 | $31,920 |
| 2025-11-13 | PERCEPTIVE ADVISORS LLC | 10% Owner | Sell | 7,862 | $31,920 |
| 2025-11-13 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | Sell | 7,862 | $31,920 |
| 2025-11-13 | Perceptive LS (A), LLC | 10% Owner | Sell | 7,862 | $31,920 |
| 2025-11-13 | EDELMAN JOSEPH | 10% Owner | Sell | 883 | $3,585 |
| 2025-11-13 | PERCEPTIVE ADVISORS LLC | 10% Owner | Sell | 883 | $3,585 |
| 2025-11-13 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | Sell | 883 | $3,585 |
| 2025-11-13 | Perceptive LS (A), LLC | 10% Owner | Sell | 883 | $3,585 |
| 2025-11-13 | EDELMAN JOSEPH | 10% Owner | Sell | 28,597 | $111,528 |
| 2025-11-13 | PERCEPTIVE ADVISORS LLC | 10% Owner | Sell | 28,597 | $111,528 |
| 2025-11-13 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | Sell | 28,597 | $111,528 |
| 2025-11-13 | EDELMAN JOSEPH | 10% Owner | Sell | 4,783 | $20,615 |
Source: SEC Form 4 filings · as of 2026-05-15