10 insiders reported 103 Form 4 transactions for Spyre Therapeutics, Inc. (SYRE) over the past 18 months (most recent 2026-09-03). Recent activity: King-Jones Heidy (See Remarks) Sell 6,206 shares, King-Jones Heidy (See Remarks) Sell 400 shares, Burrows Scott L (Chief Financial Officer) Buy 7,500 shares, Turtle Cameron (Chief Executive Officer) Sell 8,400 shares, King-Jones Heidy (See Remarks) Sell 4,845 shares. Source: SEC Form 4.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-09-03 | King-Jones Heidy | See Remarks | Sell | 6,206 | $547,183 |
| 2026-09-03 | King-Jones Heidy | See Remarks | Sell | 400 | $36,000 |
| 2026-09-03 | Burrows Scott L | Chief Financial Officer | Buy | 7,500 | $108,750 |
| 2026-09-03 | Turtle Cameron | Chief Executive Officer | Sell | 8,400 | $732,060 |
| 2026-09-03 | King-Jones Heidy | See Remarks | Sell | 4,845 | $418,608 |
| 2026-09-03 | Burrows Scott L | Chief Financial Officer | Sell | 900 | $77,625 |
| 2026-09-03 | Turtle Cameron | Chief Executive Officer | Sell | 3,700 | $325,822 |
| 2026-09-03 | King-Jones Heidy | See Remarks | Buy | 27,999 | $405,986 |
| 2026-09-03 | Burrows Scott L | Chief Financial Officer | Sell | 4,384 | $381,890 |
| 2026-09-03 | Turtle Cameron | Chief Executive Officer | Sell | 400 | $35,628 |
| 2026-09-03 | Turtle Cameron | Chief Executive Officer | Sell | 2,500 | $215,900 |
| 2026-09-03 | Burrows Scott L | Chief Financial Officer | Sell | 2,016 | $177,468 |
| 2026-09-03 | King-Jones Heidy | See Remarks | Sell | 400 | $35,752 |
| 2026-09-03 | Burrows Scott L | Chief Financial Officer | Sell | 200 | $17,808 |
| 2026-09-03 | King-Jones Heidy | See Remarks | Buy | 400 | $5,800 |
| 2026-09-03 | Burrows Scott L | Chief Financial Officer | Sell | 18,232 | $1.6M |
| 2026-09-03 | King-Jones Heidy | See Remarks | Sell | 16,548 | $1.4M |
| 2026-08-10 | Albers Jeffrey W. | Director | Buy | 5,000 | $51,950 |
| 2026-08-10 | Albers Jeffrey W. | Director | Sell | 5,000 | $522,350 |
| 2026-08-10 | Albers Jeffrey W. | Director | Sell | 10,000 | $1.0M |
| 2026-08-10 | Albers Jeffrey W. | Director | Sell | 8,000 | $835,040 |
| 2026-08-05 | Burrows Scott L | Chief Financial Officer | Sell | 5,100 | $485,571 |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 800 | $75,176 |
| 2026-08-05 | Burrows Scott L | Chief Financial Officer | Buy | 7,500 | $108,750 |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 7,157 | $680,631 |
Source: SEC Form 4 filings · as of 2026-09-03